Fig. 5.
Accumulation of neutrophils in the blood, pulmonary capillaries, and hepatic sinusoids. Complement fragments induced a significant decrease in the circulating neutrophil counts at 15 minutes and a significant increase at 30 minutes after the infusion was stopped. The neutropenia was accompanied by a significant increase in the number of neutrophils within the pulmonary capillaries. However, the number of sequestered neutrophils decreased only by 27% by 30 minutes after the infusion. In contrast, infusion of complement fragments did not induce an increase in the number of neutrophils within the hepatic sinusoids after 15 minutes, but caused a 2.3-fold increase within 30 minutes after the infusion was stopped. *Significantly different from the same organ in animals that did not receive complement fragments, P < .05. **Significantly different from the same organ in animals studied immediately after the 15 minutes of complement fragments, P < .05.