Kinetics of engraftment CML cell line and hematopoietic cells from different disease stages. Kinetics of engraftment were assessed at serial intervals after injection. Values show the median percentages of human cells in different tissues (□———□ BM, ⧫– – –⧫ blood, ○·····○ spleen) detected by human CD45 staining on four mice killed at each time point. BV173 cell line and samples from four patients in CP (CP1, CP2, CP4, CP5), two in AP (AP1, AP2), and two in BP (BP1, BP2) were injected.