Fig. 8.
Tachpyr inhibits ferritin synthesis. Cells were treated with 20 μmol/L tachpyr (tach), 150 μmol/L desferioxamine (def) or 200 μmol/L ferric nitrilotriacetate (iron) in growth medium for 16 hours. Cells were labeled with [35]S amino acids for the last 2 hours of treatment. Ferritin was isolated by immunoprecipitation and analyzed by SDS-PAGE. The H and L subunits of ferritin are shown (lower and upper bands, respectively).