The percentage of PMN^BrdU in the circulation, sinusoids, and hematopoietic tissue in the BM 60 minutes after IL-8 (n = 6) or saline (n = 3). The percentage of PMN^BrdU was higher in the hematopoietic tissue and venous sinusoids than in the circulating blood in both the IL-8 and control groups. IL-8 caused an increase in PMN^BrdU in the circulating blood (P < .05) and a decrease in the PMN^BrdU venous sinusoids (P < .05). Compared with the hematopoietic tissue, the percentage of PMN^BrdU in the sinusoids was lower in the IL-8 group (P < .05), but not in the controls. Values are mean ± SEM. *P < .05 control versus IL-8 group, #P < .05 hematopoietic tissue versus sinusoids in the IL-8 group.