Fig. 1.
![Fig. 1. (A) Hyperplastic lymph node showing BSAP expression primarily restricted to follicular regions, with strong nuclear staining present in mantle zone cells and less intense staining in follicle center cells. (B through D) Lymphomas with strong BSAP expression: (B) mantle cell lymphoma, (C) FL, and (D) mediastinal large B-cell lymphoma. (E and F) Lymphomas with no BSAP expression. (E) Primary monocytoid B-cell (MALT-) lymphoma of parotid gland and (F) angioimmunoblastic T-cell lymphoma. Note the positive control staining of residual mantle zone cells and normal B cells in the negative cases. (Streptavidin-biotin-peroxidase method; original magnification [A] ×200, [B] ×400, [C] ×200, [D] ×600, [E] ×200, and [F] ×400.)](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/92/4/10.1182_blood.v92.4.1308/5/blod41632001cy.jpeg?Expires=1735836397&Signature=CiLIQkIdpfzHL0I1sIN86oUzrhvooQPH70dzCDiLjJVv2J0XIRmFvDn087jc3qZc2ZWGqxS4WMApHAHH9Pu5NrQKLwfkWzHf78-pdDf8jRZT4Z86I~72UJ6-Oy6IfwYtbl4sgA-5SRngKep5BfOH2p~WKdVmenWrNTNSgw~qojKkTThFtUrKt59nxy-sg8s~ET-hDz6MMckWfBvPAuN7EcWk7OhEfaxCm~gpfsdHQZ7lSwcsmASZ1MYKrv8p0Ux~GhK8BYHFHOlC2TyA2VbevvZE33jCY6jxEaA9ZnlEU7tKshZf2bbvcMXkSAxDRW4Nn3AyGOsM4B568jk6EBv0Qw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
(A) Hyperplastic lymph node showing BSAP expression primarily restricted to follicular regions, with strong nuclear staining present in mantle zone cells and less intense staining in follicle center cells. (B through D) Lymphomas with strong BSAP expression: (B) mantle cell lymphoma, (C) FL, and (D) mediastinal large B-cell lymphoma. (E and F) Lymphomas with no BSAP expression. (E) Primary monocytoid B-cell (MALT-) lymphoma of parotid gland and (F) angioimmunoblastic T-cell lymphoma. Note the positive control staining of residual mantle zone cells and normal B cells in the negative cases. (Streptavidin-biotin-peroxidase method; original magnification [A] ×200, [B] ×400, [C] ×200, [D] ×600, [E] ×200, and [F] ×400.)
