Fig. 4.
LIL-Stat is transcriptionally active in 5 out of 7 AML cases. Blasts of AML cases 1 through 7 were transfected with the reporter constructs pGL3ti or pGL3ti-3LILRE together with pCMVCAT. CAT activity was used to normalize for transfection efficiency within 1 AML case. Luciferase activity obtained after transfection with pGL3ti control vector was set at 100%. Error bars represent standard deviation of at least three identical experiments (* P < .05).