Fig. 3.
Effect of forced expression of JAB and CIS3 on IFN-induced growth inhibition of M1 cells. Parental M1 cells and CIS3 or JAB transformants (5,000 cells/well) were plated in 24-well plates and cultured for 6 days in the presence of the indicated amount of IFN-β (A) or IFN-γ (B). Then the viable cells were counted by Trypan blue exclusion. The viability of the cells is expressed as the percentage of the number of IFN-treated cells to that of untreated cells. The numbers of untreated cells (100%) are 2.4 × 105 (parental M1 cells), 2.4 × 105 (JAB transformant), and 2.1 × 105 (CIS3 transformant).