American Society of Hematology

Fig. 2.

$Fig. 2. Quantitative displacement of annexin-V from the PS/PC phospholipid bilayers by aPL IgG preparations in the presence of β2-GPI cofactor. The combination of aPL IgG with β2-GPI significantly displace annexin-V from the bilayers as compared with control IgG with β2-GPI. The mean (±SEM) quantity of annexin-V displaced by three different aPL syndrome patients’ IgG fractions was 0.115 ± 0.014 μg/cm2 as compared with no significant displacement by three different control IgG preparations (0.005 ± 0.007 μg/cm2, P = .002). These data demonstrate the displacement of annexin-V from the phospholipid bilayer surface by aPL IgG in the presence of β2-GPI.$

Quantitative displacement of annexin-V from the PS/PC phospholipid bilayers by aPL IgG preparations in the presence of β₂-GPI cofactor. The combination of aPL IgG with β₂-GPI significantly displace annexin-V from the bilayers as compared with control IgG with β₂-GPI. The mean (±SEM) quantity of annexin-V displaced by three different aPL syndrome patients’ IgG fractions was 0.115 ± 0.014 μg/cm² as compared with no significant displacement by three different control IgG preparations (0.005 ± 0.007 μg/cm², P = .002). These data demonstrate the displacement of annexin-V from the phospholipid bilayer surface by aPL IgG in the presence of β₂-GPI.

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