Hematopoiesis over 8 weeks (GM-CFC and nucleated cells) in LTBMCs established from patients before (A) and after completion of six cycles of FAC chemotherapy (B). Symbol key: •, control group (n = 5); ○, BB-10010, 30 μg/kg (n = 7); ▪, BB-10010, 100 μg/kg (n = 6). Values represent the mean ± SE. Differences in the AUC between weeks 1 and 8 of culture for each patient group, pretreatment and posttreatment, groups were not statistically significant (P > .05).