Fig. 3.
Pulse-chase globin chain synthesis in an untransfused HbE/β thalassemic [IVS 1-5(G-C)] at 37°C. At time 0 minutes, the mixture was washed and the unused radiolabeled leucine was removed. The SA increases for the first 5 minutes as residual radiolabeled leucine is used and then plateaus, with no decrease in SA of the globin chains.(□) γ; (▪) βA; (•) βE; (○) α.