Fig. 5.
Effect of BAH-1 MoAb on human CFU-MK colonies. (A) CD34+ bone marrow cells were plated at 5 × 103/mL in the fibrin clot system (see the Materials and Methods). Results are expressed as the means ± SEM of megakaryocyte colonies. Experiments were performed in triplicate in four assays. *Statistically significant compared with PBS (P < .05). (B) Photographs of CFU-MK colonies in the presence of BAH-1 (B-I) or TPO (B-II).