Fig. 3.
As2O3 and melarsoprol induce apoptosis in NB4, HL60, and U937 cell lines. Apoptotic cells were identified by the in situ TdT assay, as well as morphological changes of nuclei after DAPI staining. The percentages of TUNEL-positive cells (A) and cells with nuclear fragmentation (B) were expressed as the mean ± SD. Morphology of TUNEL-positive cells are indicated with black arrows and fragmented nuclei are indicated with white arrows, as shown in panels (C) and (D).
