Time course of lysis of plasma clots by scuPA/suPAR.¹²⁵I-labeled clots prepared from plasma were overlaid with serum and incubated with 25 nmol/L scuPA in the presence (solid symbols) or absence (open symbols) of equimolar concentrations of suPAR for 210 minutes at 37°C. The radioactivity released into the supernatant was measured. The clots were overlaid with serum (▧ and □) or PBS (△ and ▵), which contained either scuPA alone (□ and ▵) scuPA/suPAR (▧ and △), suPAR alone (◍) or scuPA/suPAR + 250 nM ATF in PBS (*). The mean ± SEM of three experiments is shown.