Fig. 3.
Examples of FISH experiments performed on case no. 1 (A through D), case no. 2 (E), and case no. 3 (F). Applied probes included ALK P1 (red) and 5q35 cosmids (green) (A), 86J13 (2psubtel) (B), LSI ALK (5′ end of ALK [green]; 3′ end of ALK [red]) (C), ALK P1 (red) and 914E7 (green) (D through F), and D2Z (red) (E). Long arrows, short arrows, and arrowheads indicate the normal chromosomes 2, inv(2)(p23q35), and i(2)(q10), respectively.