Structures of the AML1/Evi-1 protein and its derivatives are compared with Evi-1. ▵ZF1-7 is a deletion mutant of AML1/Evi-1 that lacks the first zinc finger domain of Evi-1, while ▵Rep is a mutant lacks the repression domain of Evi-1. Distinct functional domains of AML1/Evi-1 are presented. Zinc finger motifs are numbered 1-10.