Fig. 5.
Comparison of the apoptotic potential of As2O3 and antimonials on RA-sensitive and -resistant APL cells and U937 cells. NB4, NB4R4, or U937 cells were incubated for 24 or 48 hours with 1 μmol/L As2O3, 1 μmol/L Sb2O3, or 1 μmol/L PAT, and the percentage of apoptotic cells was determined by Hoechst 33258 staining. Untreated cells were used as control.