Fig. 6.
Ratio of Ph+ cells to Ph−cells. Ph chromosomes were found in myeloid cells and B lymphocytes but not in mature T and NK cells. BCR/ABL fusion signals were found in pluripotent stem cells (CD34+Thy-1+), B progenitor cells (CD34+CD19+), and T progenitor cells (CD34+CD7+ cells or CD34+CD7+CD5+) at a frequency equal to that in all CD34+ cells. T lymphocytes showed a marked decrease of Ph+ cells between progenitor cells and mature cells. The incidence ratios of Ph+ cells in mature T cells and NK cells were below the cutoff value.