Fig. 8.
Increased tumor-specific CTL activity in mice bearing L1210 Fas+ but not L1210 Fas− cells. Purified T cells from DBA/2 mice bearing L1210 Fas+ or L1210 Fas− tumor cells were obtained and cultured with irradiated L1210 Fas+ and Fas− tumor cells, respectively, for 5 days. Next, the harvested cells were tested for cytotoxicity against L1210 Fas+ or Fas−tumor targets (A) or against P815 (B) as described in Fig 4. In the symbols, the first column represents source of T cells, the second shows stimulator cells, and the third depicts target cells tested. For example, Fas+ / Fas+ / Fas+represents T cells from mice bearing Fas+ tumor cells stimulated with Fas+ tumor cells in vitro and tested for cytotoxicity against Fas+ targets.