Fig. 1.
Effect of exposing cells to DT388-GM-CSF in liquid culture for 48 hours followed by measurement of the remaining progenitor activity in semisolid assays. (A through C) Cells from representative CMML patients; (D) cells from normal marrow samples and HL60 cells (plated at 2 × 104 cells/dish); (E) cells from a representative JMML patient. (A) (⧫), KP; (▴), RM; (•), SB; (▪), EB. (B) (◊), ED; (▵), LP; (○), WB; (□), FB. (C) (⧫), PP; (▴), GW; (•), GN; (▪), DJ. (D) (⧫), U11811; (▴), U11454; (•), U11802; (▪), HL60; (E) (•), AJ.