2-5A–anti-bcr treatment of K562 cells leads to decreased levels of p210^bcr-abl kinase activity and cell growth inhibition. (A) An autoradiogram and (B) results of phosphorImage analysis of the gel from a p210^bcr/abl kinase activity assay measured from K562 cells treated with different ODNs as indicated in the figure and described in Materials and Methods. (C) Effects on K562 cell growth and survival of ODN treatments. Cells were seeded at 10⁵ cells per well at time 0 and counted after 40 hours of ODN treatment (y-axis).