Fig. 7.
The ability of mouse bone marrow cells from WT and βc-null mice to take up the glucose analogue 3H-2-DOG after incubation in GM-CSF (concentration range, 500 to 50,000 U/mL) or carrier. Cells were incubated in 2-DOG and then 3H-2-DOG, 1 μCi per 1 mL culture, was added for 10 minutes’ incubation at 37°C. The fold change in glucose uptake after incubation in GM-CSF compared with carrier was calculated for each cell preparation. Results are means of 14 WT mice and 22 βc-null mice. Error bars represent SD.