Fig. 1.
Mapping of deletions and a translocation involving chromosome bands 7q31-qter in 13 myeloid leukemias by FISH. HSC7E-YACs are from the chromosome 7–specific YAC library17 and the C_row_plate_ column YACs are from the CEPH-Généthon collection.21 Clones HSC7E248 to HSC7E113 recognize a contiguous genomic fragment in chromosome bands 7q35-q36. del, deletion (only one fluorescence signal); t, translocation breakpoint; di, disomy (two fluorescence signals indicating retention of both alleles); empty boxes, not done; light gray boxes, extent of the deletion; dark gray boxes, commonly deleted segment.