Fig. 7.
Effect of the PKC inhibitors BIM and Gö 6976 on activation of the LTR. The reaction mixture contained 2 × 106 Jurkat LTRluc and where indicated 100 ng/mL PMA, 10−4 mol/L H2O2, 106 neutrophils/mL, 100 U of TNF-/mL, and BIM and Gö 6976 at the concentrations indicated in RPMI at a final volume of 2.0 mL. The results are the mean + (Gö 6976) or − (BIM) SEM of four experiments with the asterisk indicating a significant difference from the absence of the PKC inhibitors (P < .05).