Fig. 5.
Survival data of lethally irradiated (8.75 Gy) recipient mice for at least 4 weeks after transplantation of LFA-1 sorted cytokine-mobilized blood cells. Donor mice were pretreated with daily IP injections of 5 μg G-CSF for 3 days or a single IP injection of 30 μg IL-8. With G-CSF, a total number of 1.5 × 105 MNC (LFA-1tot), 1.5 × 105 LFA-1pos, and 12,750 LFA-1neg cells were transplanted and with IL-8, a total number of 5 × 105 LFA-1pos and 25,000 LFA-1neg cells were transplanted. Survival data are expressed as percentages of 10 mice transplanted per group in one experiment.