Thrombin generation in PRP of a patient with severe (type III) deficiency of vWF. (▴) patient’s PRP with 2.5% recombinant FVIII added; (▵) patient’s PRP with 2.5% normal PPP added; (+) patient’s PRP with 2.5% normal PPP and with a frozen and thawed suspension of normal platelets added at t = 90 s; (•) patient’s PRP with 2.5% normal PPP and with a frozen and thawed suspension of the patient’s platelets. The final concentration of platelet material was equivalent to 2 × 10⁷ platelets/mL.