Response to Total Therapy in relationship to the individual treatment components, depicting ≥PR by the stippled columns and CR by the shaded bars. (A) Intent-to-treat analysis including all 231 patients enrolled. PR and CR rates increased steadily with the progression through the different phases of Total Therapy. PR and CR rates are depicted in a cumulative fashion, regardless of whether the individual treatment components were actually administered. (B) PR and CR increments among the 165 patients who actually completed two transplants (128 of 151 tandem autotransplant recipients also started IFN).