The effect of MoAb treatment on croton oil-induced ear swelling throughout the response. (A) The change in ear swelling of L-selectin–deficient mice. At each time point, mice treated with combined anti-P_B plus anti–E-selectin are significantly different from each of the other treatment groups (all pairwise comparisons P < .001). (B) The change in ear swelling of wild-type mice. Anti-P_B- plus anti–E-selectin inhibits ear swelling at each time point (P < .005 compared with no antibody control), whereas anti–L-selectin has no effect. Data are from a representative experiment (n ≥ 3 mice/time point).