Fig. 5.
CCR-1 and CCR-3 are involved in clustering of monocyte-derived DCs with TCs. TCs purified from PBMCs (105) were cultured with monocyte-derived DCs (104) in the absence (A) or presence of 10 μg/mL cont. IgG (B), anti–CCR-1 MoAb (C), or anti–CCR-3 MoAb (D). The coculture of monocyte-derived DCs with TCs was measured on day 5. Original magnification × 200. The results are representative of two experiments performed with similar results.