B-CLL cells of patients with differing survival differ in their expression levels of CD45 and CD49d. (A) Mean fluorescence of CD45 and CD49d on B-CLL cells of all patients (with or without 11q deletion) and on B-CLL cells with 11q deletion separated into groups of cells of (□) patients who are alive and (▩) patients who died. Marked by the box diagram are the 10th, 25th, 50th (median), 75th, and the 90th percentiles. (○) Values below or above the 10th and 90th percentile, respectively. (B) Kaplan-Meier curves of the overall survival of all patients with B-CLL (with or without 11q deletion) separated into groups of CD45^{high-positive} (>425 mean fluorescence), CD45^low-positive (≤425 mean fluorescence), CD49d^low-positive (>2.9 mean fluorescence), and CD49d^negative (≤2.9 mean fluorescence) expression levels on the B-CLL cells. Tick marks represent censored data on patients who were alive or lost to follow-up.