Fig. 1.
![Fig. 1. IL-10 suppression of SEB stimulation: SEB dose-response. PBMCs were added to 96-well plates at 3 × 105 cells/mL along with IL-10 at 10 U/mL or media only. After 2 days of incubation, media alone or SEB at varying concentrations was added and plates were further incubated for another 2 days. Proliferation was measured by [3H]thymidine incorporation. Different PBMC donors are represented in each experiment. Data are expressed as the mean CPM ± SD. Results were determined to be statistically significant by the Student’s t-test (P < .002). Numbers between curves indicate the percentage of suppression by IL-10.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/93/1/10.1182_blood.v93.1.208/5/blod40106001x.jpeg?Expires=1735539644&Signature=kemKB4JFAWdK8lYGJ4ssTjycRN5iTlgpuIT1aDMx6u3QjCuSCUl3rAgbh~LwmgCXK-I~du9val7wa4LrHHqDCLD8H8mtbWCUd5GDrqSUPHF6NvoW3TB7cpCyBIxYcoCveh54mgHcnuj5Pb5tPgFgOIC10~LxqE5rNBHxfm40gIy2YwXX4sUgEU16U~Mr2uYbyXrdfqQjEu8OihFd56jspW3bVDSPWICTqZwVYVt1RZC~WgaDHUAJr8LM50EcMrRVg-hmihMjbSy53K0zkmMiJMIr4zgqcRU9nYUfsM3EDQCmVN5ot1vXlc85Qh5VofGPYsu7s455KaFaYzLoMRJ4Ng__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
IL-10 suppression of SEB stimulation: SEB dose-response. PBMCs were added to 96-well plates at 3 × 105 cells/mL along with IL-10 at 10 U/mL or media only. After 2 days of incubation, media alone or SEB at varying concentrations was added and plates were further incubated for another 2 days. Proliferation was measured by [3H]thymidine incorporation. Different PBMC donors are represented in each experiment. Data are expressed as the mean CPM ± SD. Results were determined to be statistically significant by the Student’s t-test (P < .002). Numbers between curves indicate the percentage of suppression by IL-10.
