The inhibitory effect of HDS on SS RBC adhesion in the mesocecum microvasculature. (A) Vessels show clear lumen during perfusion with Ringer-albumin (a, arteriole; v, venule). Bolus infusion of HDS-treated SS RBC results in rapid flow of these cells (B) with no resulting adhesion after the passage of the bolus (C). When untreated SS RBC are infused (D), their passage is accompanied by a variable extent of adhesion in venular segments depicted by small arrows. (E) Higher magnification of the area indicated by small arrows in D shows adhesion of SS RBC. The large arrows indicate the flow direction. Bars = 30 μm.