(A) ANUP inhibits angiogenesis in CAM assays. Filter disks soaked in buffer alone, bFGF alone, or bFGF and test compounds in a total volume of 10 μL were used on 10-day-old CAMs. CAMs harvested after 48 hours were resected and photographed, and the number of branching blood vessels was counted within the area of each disk. The assay represents the mean ± SE of ≥8 CAMs per test group. Assays were repeated at least twice, with similar results. (B) Representative photographs (original magnification ×40) of control group receiving buffer only, bFGF alone (200 ng), and bFGF plus ANUP (0.1 μg).