Fig. 4.
Representative photomicrographs depicting the effects of antiasialo GM1 antibody on inhibition of bFGF-induced neovascularization by IL-12. Female BALB/c mice were injected subcutaneously with Matrigel alone (A), Matrigel impregnated with bFGF alone (B), bFGF + IL-12 (C), bFGF + antiasialo GM1 antibody (D), or bFGF + antiasialo GM1 antibody + IL-12 (E). Matrigel plugs were removed 7 days after injection and were processed for histology. The sections were stained with Masson’s trichrome. Original magnification ×20.