Fig. 2.
Localization of the oxidase to the neutrophil plasma membrane.34 Normal neutrophils were activated and unroofed, and the cytoplasmic face of the plasma membrane was labeled by the immunogold technique with anti-p67PHOX (large beads) and anti-gp91PHOX (small beads). The oxidase assemblies are gathered together in small clusters. Similar results were obtained with anti-p67PHOX/anti-p47PHOX and anti-p67PHOX/anti-Rac antibody pairs. (Reprinted with permission.34)