Fig. 1.
Influence of antiplatelet GP MoAbs on megakaryocyte colony formation. Peripheral blood nonadherent mononuclear cells (2.5 × 105 cells/mL) were cultured in IMDM supplemented with 10 ng/mL TPO, 10 ng/mL SCF, and 1 μg/mL each antiplatelet GP MoAb for 14 days. The number of colonies (A) and colony size (B) were counted using an inverted microscope. The data are the means ± standard error of mean (SEM) from duplicate cultures in two experiments using cells from three donors. *Significantly different compared with the controls (P < .05).