Fig. 2.
(A) Expression of OB-R in normal bone marrow (NBM), normal peripheral blood (NPB) and sorted myeloid progenitors (CD34+, CD34−33+, CD34−13+) from adult bone marrow. The MO7E cell line served as a positive control. (B) OB-Rexpression in FACS-sorted CD34+ cells from normal bone marrow, AML, and chronic myeloid leukemia in blast crisis (CML-BC). β2-M, β2-microglobulin; OB-Rl, long isoform (501 bp); OB-Rs, short isoform (720 bp); M, molecular-weight marker.