Fig. 3.
![Fig. 3. Inhibition of the proliferation of cytotoxic tyrosinase-specific CD8+ T cells by IL-10–treated DC. Tyrosinase-specific, cytotoxic CD8+ T cells were cultured with the specific tyrosinase peptide, either in combination with HLA.A2+ DC pretreated with IL-10 or untreated. In control experiments, the unspecific peptide MART-1 was added to the culture. Proliferation was measured by incorporation of [3H] TdR after 3 days of culture. The results represent one of three experiments.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/93/5/10.1182_blood.v93.5.1634/4/blod40511003x.jpeg?Expires=1735540926&Signature=0-pHOxjPdhcZwf9Yg50TuFH3Az2rQyuFC51FtLzo-L2Hx12g-n2raMba~L6IosrVMMumJ1my4kQsDdW1hlo~vx4eMetPfqXpD1ccSlQPDKuPbiSfMErAtoWlOF6k6YlI8JuRnc1zhyLBHsrmm7dW3MqFSiz92e7lUnkbK1k6hKdfPeTxQc4kAjgcKNQt6tcdDJ~-j07JBW1znI65cqrsAp5RUGT6Y~4fBpoLsv9LhUxsvKAyaU96SoIKiv6Epsf7O0jxT20gi4RF1INuhKvA~uVlx0~FrtA8KRXVG6Bn2Py4HEqFXnLyst5IMCCTN2RoJUPB8m8Xv-nXIOHjXJfBDw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Inhibition of the proliferation of cytotoxic tyrosinase-specific CD8+ T cells by IL-10–treated DC. Tyrosinase-specific, cytotoxic CD8+ T cells were cultured with the specific tyrosinase peptide, either in combination with HLA.A2+ DC pretreated with IL-10 or untreated. In control experiments, the unspecific peptide MART-1 was added to the culture. Proliferation was measured by incorporation of [3H] TdR after 3 days of culture. The results represent one of three experiments.
