Fig. 2.
Distribution of MTX metabolites (MTX-Glu1-6) expressed as mean value pmol MTX-Glun/109 cells (±SE) for 40 c/preB-ALL (□), 13 T-ALL (▨), and 14 AML (▪) patients. Leukemic cells were incubated for 24 hours with 1 μmol/L [3H]-MTX as described in Materials and Methods.