Effect of PKC inhibitors on Dex-induced apoptosis and signaling pathway. Effect of H7 and calphostin-C on (A) Dex-induced apoptosis, (B) DAG, and (C) ceramide generation. Thymocytes were treated with Dex (10⁻⁷ mol/L) for the indicated times in the presence or absence of H7 (50 μmol/L) or calphostin-C (1 μmol/L).