Fig. 5.
L-selectin expression on BrdU-labeled PMN transferred from the donors into the circulation of recipients after IV injection of either 2.0 mg/kg dexamethasone (n = 5) or saline (n = 4) at baseline (A) and 12 hours after treatment (B) using the immunocytochemical grading system (see Materials and Methods). Values are expressed as the means ± SEM. At baseline, L-selectin expression was similar in both groups. Twelve hours after treatment, there was a significant decrease in the L-selectin expression in both groups. However, this decrease was larger in the controls than the dexamethasone-treated rabbits. *P < .01 compared with baseline; †P < .05 compared with baseline; ‡P < .01 compared with control; Dex, dexamethasone.