Fig. 2.
Fig. 2. PGE2 downregulated JAK3 expression in primed T cells. CD3+ peripheral blood lymphocytes were cocultured with PHA for 3 days. Primed cells were then cultured for 24 hours with medium IBMX, PGE2, or PGE2 plus IBMX before performing a Western blot to detect JAK1, JAK3, p59fyn, or p56lck. Representative data are presented.

PGE2 downregulated JAK3 expression in primed T cells. CD3+ peripheral blood lymphocytes were cocultured with PHA for 3 days. Primed cells were then cultured for 24 hours with medium IBMX, PGE2, or PGE2 plus IBMX before performing a Western blot to detect JAK1, JAK3, p59fyn, or p56lck. Representative data are presented.

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