Changes in CDR3 size patterns associated with achievement of stable remission off CyA therapy. CDR3 size patterns of patient no. 5 (P5) at the time of unmaintained remission after 4 years of CyA therapy and patient no. 8 (P8) in CyA-dependent remission after 7 years of therapy were compared with patterns at the time the disease was active. A, before CyA therapy; B, after CyA therapy.