Effects of mitomycin C and anti-CD95 in CD95-sensitive and resistant Jurkat cells. 3 × 10⁴ CD95-sensitive (Jurkat; ——, ⧫) or resistant cells (Jurkat-R; -----, ◊) were stimulated with (A) mitomycin C or (B) agonistic anti-CD95 antibodies at the indicated concentrations for 24 hours. Cells in the absence of apoptotic stimuli were treated with the diluent of the respective highest drug concentration. Induction of apoptosis was assessed by propidium iodide staining of hypodiploid apoptotic nuclei and subsequent flow cytometry.