Sequence variability and similarity between the nucleotides 893 to 1226 of the ORF26 of HHV-8 genome among HHV-8⁺ samples from 6 patients with POEMS syndrome, 1 HIV-infected patient with Kaposi’s sarcoma (KS) and multicentric Castleman’s disease (MCD) (patient KS/MCD), and 8 healthy African blood donors (ABD). Only nucleotides of the 11 identified variable positions are included. All nucleotides at the other unvariable positions are similar to those reported in the original sequence KSHV AIDS (GenBank U40377) initially published by Chang et al.3The positional nomenclature used for ORF26 follows that of Chang et al.3 Bold and underlined nucleotide substitutions at positions 1032, 1033, and 1132 (patients with POEMS syndrome) and 981 (patient KS/MCD) lead to amino acids changes. BM, bone marrow; LN, lymph node; Myel, myeloma.