Fig. 5.
T20/DP178 analogs attenuate fMLP- or T20/DP178-induced Ca2+ mobilization. Monocytes (A) or ETFR cells (B) were loaded with Fura-2 and then were sequentially stimulated with T20/DP178 analogs T719 or T712 (50 μmol/L) and fMLP (100 nmol/L) or T20/DP178 (100 nmol/L). Chemokine MCP-1 (100 nmol/L) was used to indicate the specificity of T719 or T712 (A).