Kaplan-Meier survival curves for 386 myeloma patients separated by low (0 to 9 μg/L, n = 20), intermediate (10 to 120 μg/L, n = 315), and high (>120 μg/L, n = 51) HYA value. The survival difference between the abnormally low or high and the intermediate HYA level group were significant (P = .005).