Fig. 4.
(A) Cytogenetic analysis of spleen cells from a CY-treated mouse with LOH at Nf1 shows a normal diploid karyotype. (B) FISH of the same specimen shown in (A) with a genomicNf1 probe shows 1 copy of the gene on each chromosome 11 homolog.
(A) Cytogenetic analysis of spleen cells from a CY-treated mouse with LOH at Nf1 shows a normal diploid karyotype. (B) FISH of the same specimen shown in (A) with a genomicNf1 probe shows 1 copy of the gene on each chromosome 11 homolog.
