Fig. 2.
Deletion-deficient chimera-derived T cells proliferate in response to host type APC. A total of 5 × 105 Splenocytes or 106 thymocytes were stimulated with titrated numbers of T-cell–depleted, irradiated splenocytes. Origin of effectors and APC was as indicated in the figure. Exogenous IL-2 was added to thymocyte and splenocyte cultures unless indicated otherwise.3H-thymidine incorporation was assessed 3 to 4 days later.