Fig. 1.
(A) MB361 chemotherapy schema. Bone marrow aspirate for stroma culture was obtained before the first cycle of chemotherapy. Vinblastine was substituted for doxorubicin after patients exceeded a lifetime cumulative doxorubicin dose of 550 mg/m2. (B) A diagram of the PCR assay showing the position of the primers used to detect the MDR1 transgene and the relative positions of their annealing sequences on the human genome. The numbering system shows that of the G1MD vector. The MDR1 cDNA starts at nt 1479 and ends at nt 5339. The MDR1 ATG start codon is at position 1491.
