Fig. 5.
Expression of Fas on donor and host T-cell subsets. A cell suspension containing 6 × 107 B6.SJL T cells was injected into unirradiated B6AF1 recipients. (A) Increased Fas expression on day 8. Three-color staining was performed with the following antibodies: FITC-labeled anti-Ly5.1 or anti-Ly5.2, Cy-chrome–labeled anti-CD4 or anti-CD8, and PE-labeled anti-Fas (shaded histogram) or its isotypic control (clear histogram). Results from one representative experiment of three are shown. (B) Time course evaluation of Fas expression. Mean ± SD, N = 3; nd, not done. *P < .05, **P < .01, ***P < .005 relative to control.
